One-quarter of Alzheimer’s patients developed delirium during a hospital admission, a prospective registry study found. About one in eight patients were put in a care facility, further declined cognitively, or died within one year as an adverse outcome attributable to an episode of in-hospital delirium, according to Tamara G. Fong, MD, PhD, of the Aging [...]
Women Have Higher Genetic Risk of Alzheimer’s
A major genetic risk factor for Alzheimer’s disease – the E4 variant of the apolipoprotein E (APOE) gene — manifests itself more often in women than in men, researchers reported. In a cohort of cognitively healthy older men and women, carrying the E4 variant was associated with deficits in brain connectivity in women, but not [...]
Onslaught of Dementia Lies Ahead
The number of cases of dementia is increasing dramatically, and governments around the world are unprepared for it, a health conference in Charlottetown heard Monday. The number of people living with dementia will double by 2030, says Barry Greenberg of the Toronto Dementia Research Alliance. (CBC) Barry Greenberg of the Toronto Dementia Research Alliance told the [...]
Beta Amyloid May Be The Key To Diagnosis Of Alzheimer’s In Healthy Patients
New research from Rhode Island Hospital has revealed a link between brain insulin resistance (diabetes) and two other key mediators of neuronal injury that help Alzheimer’s disease (AD) to propagate. The research found that once AD is established, therapeutic efforts must also work to reduce toxin production in the brain. The study, led by RI Hospital researcher [...]
Fear Grips a Family
In a clinical trial that could lead to treatments that prevent Alzheimer’s, people who are genetically guaranteed to develop the disease — but who do not yet have any symptoms — will for the first time be given a drug intended to stop it, federal officials announced Tuesday. Experts say the study will be one [...]
What Happens To The Brain in Alzheimer’s Disease?
People with AD gradually suffer memory loss and a decline in thinking abilities, as well as major personality changes. These losses in cognitive function are accompanied by changes in the brain, including the build-up of amyloid plaques and tau-containing neurofibrillary tangles, which result in the death of brain cells and the breakdown of the connections [...]
Alzheimer’s Disease: Discussing the Diagnosis
‘When you learn that your loved one has Alzheimer’s disease or a related dementia, you might be torn between keeping it to yourself and telling others. On one hand, shouldering this responsibility alone can be overwhelming. Yet, your concerns about other people’s responses may make you hesitant to reveal the diagnosis to family, friends, and, [...]
1 in 7 People With Alzheimer’s Lives Alone
One in seven people with Alzheimer’s disease lives alone. This is one of the more stark findings from the 2012 Alzheimer’s Disease Facts and Figures, an annual report released by the Alzheimer’s Association. The new report also looks at the costs of caring for people with Alzheimer’s and other types of dementia. In 2012, this cost [...]