Archives for December 2014

Why Do So Many People with Alzheimer’s Disease Appear to be Seeing Things Incorrectly?

(Alzheimer’s Society) Alzheimer’s disease (AD) is often (but mistakenly) defined as simply a memory or cognitive disorder, but the true picture is more complicated. Alzheimer’s disease is more accurately described as a visual-perceptual-cognitive disorder. Failing to understand the complexities of the illness can lead to many misunderstandings about the difficulties that people with dementia can face. […]

The Dementia That Is Not Alzheimer’s Disease

(Science Daily) Lewy body dementia (LBD) — a complex, challenging and surprisingly common brain disease — is often misdiagnosed as its “cousin,” Alzheimer’s disease. And that could lead to devastating results. According to the Lewy Body Dementia Association (LBDA), accurate and early diagnosis is critical because people with LBD typically have sensitivities to medication, and […]

New Research Suggests an Existing Drug, Riluzole, May Prevent Foggy ‘Old Age’ Brain

(Rockefeller University) Forgetfulness, it turns out, is all in the head. Scientists have shown that fading memory and clouding judgment, the type that comes with advancing age, show up as lost and altered connections between neurons in the brain. But new experiments suggest an existing drug, known as riluzole and already on the market as […]

Memory Loss Associated with Alzheimer’s Reversed: Small Trial Succeeds Using Systems Approach to Memory Disorders

(University of California, Los Angeles, Health Sciences) Patient one had two years of progressive memory loss. She was considering quitting her job, which involved analyzing data and writing reports, she got disoriented driving, and mixed up the names of her pets. Patient two kept forgetting once familiar faces at work, forgot his gym locker combination, […]

Target Risk Factors for Dementia Prevention

Int J Geriatr Psychiatry. 2014 Dec 12. doi: 10.1002/gps.4245. [Epub ahead of print] Target risk factors for dementia prevention: a systematic review and Delphi consensus study on the evidence from observational studies. Deckers K1, van Boxtel MP, Schiepers OJ, de Vugt M, Muñoz Sánchez JL, Anstey KJ, Brayne C, Dartigues JF, Engedal K, Kivipelto M, Ritchie K, Starr JM, Yaffe K, Irving K, Verhey FR, Köhler S. Abstract OBJECTIVE Dementia has a multifactorial etiology, […]

Use of Dextromethorphan in Adults with Neurological Damage Conditions

Drugs. 2014 Nov 25. [Epub ahead of print] Dextromethorphan/Quinidine: A Review of Its Use in Adults with Pseudobulbar Affect. Yang LP1, Deeks ED. Abstract Fixed-dose dextromethorphan/quinidine capsules (Nuedexta®) utilize quinidine to inhibit the metabolism of dextromethorphan, enabling high plasma dextromethorphan concentrations to be reached without using a larger dose of the drug. The drug combination is the […]

Scientists Locate ‘Homing Signal’ in the Brain, Explaining Why Some People are Better Navigators

(University of London) The part of the brain that tells us the direction to travel when we navigate has been identified by UCL scientists, and the strength of its signal predicts how well people can navigate. It has long been known that some people are better at navigating than others, but until now it has […]

Depression in Dementia More Common in Community Care, Study Finds

(The University of Manchester) A University of Manchester study of over 400 people in eight EU countries with severe dementia has found that those residing in long-term care homes are less likely to suffer from depressive symptoms than those living in the community. Researchers studied 414 people with severe dementia along with their carers in England, Estonia, […]