Brain Injury May Boost Risk of Alzheimer’s Earlier in Life

(UT Southwestern Medical Center) Concussions and other traumatic brain injuries may increase the risk of developing Alzheimer's disease earlier in life, according to a study from UT Southwestern's Peter O'Donnell Jr. Brain Institute. The research -- the first to use autopsy-confirmed cases of Alzheimer's disease to examine the long-term effects of head injuries -- supports a correlation that … [Read More...]


Leafy Greens Linked with Slower Age-related Cognitive Decline

(NIA) A recent report in the journal Neurology found that a diet containing approximately one serving of green leafy vegetables per day is associated with slower age-related cognitive decline. Dr. Martha Clare Morris and colleagues from Rush University in Chicago and the Tufts Human Nutrition Research Center in Boston followed 960 older adults enrolled in the Rush Memory and Aging … [Read More...]

Free Alzheimer’s Tool Lets People 50 and Older Monitor Their Risk Over Time

(University of Southern California) An online tool that helps older people monitor their brain health has been developed at the Keck School of Medicine of USC with other medical groups. The free website addresses a major obstacle to finding early Alzheimer's treatments for a disease that affects more than 5 million Americans: significant delays in clinical trial enrollment. "Alzheimer's … [Read More...]

Daytime Drowsiness Increases Risk of Alzheimer’s in Elderly

(CNN) Poor sleep and the risk of dementia go hand in hand, but no one knew which came first. In what researchers say is the first study of its kind, a study published Monday in the journal JAMA Neurology shows that excessive daytime sleepiness in cognitively normal elderly leads to a buildup of a plaque in the brain called amyloid. "We know that sleep is necessary to clear toxins and … [Read More...]

FDA Opens Potential New Path for Alzheimer’s Disease Treatments

(Bloomberg Technology) The U.S. Food and Drug Administration (FDA) has issued draft guidance meant to spur the development of treatments for five neurological disorders, including early Alzheimer's disease. The guidance provides details for researchers to best approach drug development and "is a clear statement that the FDA understands that the science of Alzheimer's has evolved," said Maria … [Read More...]

Poor Fitness Linked to Weaker Brain Fiber, Higher Dementia Risk

(UT Southwestern Medical Center) Scientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer’s disease. In particular, a new study from UT Southwestern’s O’Donnell Brain Institute suggests that the lower the fitness level, the faster the deterioration of vital nerve fibers in the brain. This deterioration results in cognitive … [Read More...]


Do Memory Problems Always Mean Alzheimer’s Disease?

(NIA) Many people worry about becoming forgetful. They think forgetfulness is the first sign of Alzheimer’s disease. But not all people with memory problems have Alzheimer’s. Other causes for memory problems can include aging, medical conditions, emotional problems, mild cognitive impairment, or another type of dementia. Age-Related Changes in … [Read More...]

Enhancing Daily Life: Choosing Activities for a Loved One with Alzheimer’s

(Alzheimer's Association) A person with Alzheimer's or other dementia doesn't have to give up the activities that he or she loves. Many activities can be modified to the person's ability. In addition to enhancing quality of life, activities can reduce behaviors like wandering or agitation. Choosing Activities In the early stages of dementia, the … [Read More...]

Dementia & Driving: Help from the Alzheimer’s Association

(Alzheimer's Association) Driving demands quick reaction time and fast decision making — because of this, a person with Alzheimer's will eventually become unable to drive. Dealing with the issue early on can help ease the transition. Having the Conversation Losing the independence driving provides can be upsetting. It is important to acknowledge … [Read More...]

Joy in Caregiving: Have Fun with Your Loved One

(AARP) As caregivers we are so focused on health care, safety, finances and logistics that we can easily lose sight of quality of life — both for those we care for and for ourselves. Experiencing joy while caregiving isn’t always easy, but I believe it’s more than just a nice thing to do: It’s a crucial survival skill. Every moment of joy fills our … [Read More...]

Advance Care Planning: Getting Your Affairs in Order

(National Institute on Aging) Ben's Story Ben has been married for 47 years. He always managed the family’s money. But since his stroke, Ben is not able to walk or talk. His wife, Shirley, feels overwhelmed. Of course, she’s worried about Ben’s health. But, on top of that, she has no idea what bills should be paid or when they are … [Read More...]


Cardiorespiratory Fitness and White Matter Integrity in Mild Cognitive Impairment

J Alzheimers Dis. 2018;61(2):729-739. doi: 10.3233/JAD-170415. Cardiorespiratory Fitness and White Matter Neuronal Fiber Integrity in Mild Cognitive Impairment. Ding K1, Tarumi T1,2, Zhu DC3, Tseng BY4,2, Thomas BP5, Turner M2, Repshas J2, Kerwin DR6, Womack KB1,7, Lu H5, Cullum CM1,7, Zhang R1,4,2. Abstract Background Mounting evidence showed the self-reported levels of physical activity are positively associated … [Read More...]

Contribution of Alcohol Use Disorders to the Burden of Dementia

Lancet Public Health. 2018 Feb 20. pii: S2468-2667(18)30022-7. doi: 10.1016/S2468-2667(18)30022-7. [Epub ahead of print] Contribution of alcohol use disorders to the burden of dementia in France 2008-13: a nationwide retrospective cohort study. Schwarzinger M1, Pollock BG2, Hasan OSM3, Dufouil C4, Rehm J5; QalyDays Study Group. Abstract Background Dementia is a prevalent condition, affecting 5-7% of people aged 60 … [Read More...]

Can Exercise Improve Cognitive Symptoms of Alzheimer’s Disease?

J Am Geriatr Soc. 2018 Jan 24. doi: 10.1111/jgs.15241. [Epub ahead of print] Can Exercise Improve Cognitive Symptoms of Alzheimer's Disease? A Meta-Analysis. Panza GA, Taylor BA, MacDonald HV, Johnson BT, Zaleski AL, Livingston J, Thompson PD, Pescatello LS. Abstract Objectives To examine the effects of exercise training on cognitive function in individuals at risk of or diagnosed with Alzheimer's … [Read More...]

Effect of Aerobic Exercise on Hippocampal Volume in Humans

Neuroimage. 2018 Feb 1;166:230-238. doi: 10.1016/j.neuroimage.2017.11.007. Epub 2017 Nov 4. Effect of aerobic exercise on hippocampal volume in humans: A systematic review and meta-analysis. Firth J, Stubbs B, Vancampfort D, Schuch F, Lagopoulos J, Rosenbaum S, Ward PB. Abstract Hippocampal volume increase in response to aerobic exercise has been consistently observed in animal models. However, the evidence from human … [Read More...]