Welcome

DementiaToday posts scientific news and professional views on Alzheimer’s disease and other dementias from the global research community. We hope to promote better health care through education, provide support to caregivers and loved ones who live with these diseases everyday, and thank the many individuals around the world who are dedicated to neurological research and […]

IN THE SPOTLIGHT

Dementia Study Finds Failure to Reduce Antipsychotic Drug Prescribing

(Coventry University) A study by five universities has found that there was no sustained reduction in the prescribing of antipsychotics to dementia patients in UK care homes following the government's 2009 National Dementia Strategy (NDS), which recommended a review of their use in light of potential serious side effects. The research -- led by Professor Ala Szczepura at Coventry University and … [Read More...]

DAILY NEWS

The Shape-Shifting Protein Behind Alzheimer’s Disease

(Washington University in St. Louis) Researchers have known that the peptide amyloid beta plays a role in causing Alzheimer's disease, but they are still working to determine how it becomes toxic. Jan Bieschke, a biomedical engineer at Washington University in St. Louis, and collaborators in Germany have found that amyloid beta must change its internal structure into a long, flat structure … [Read More...]

Genetic ‘Switch’ Identified as Potential Target for Alzheimer’s Disease

(Imperial College London) A team at the MRC Clinical Sciences Centre (CSC), based at Imperial College London, has found an important part of the machinery that switches on a gene which may protect against Alzheimer’s Disease. Working in collaboration with scientists at the Hong Kong University (HKU) and the Erasmus University in Rotterdam, CSC associate professor Richard Festenstein explored … [Read More...]

Online Advice for Preventing Alzheimer’s Disease Often Problematic

(Journal of Alzheimer's Disease) New University of British Columbia (UBC) research finds that many online resources for preventing Alzheimer’s disease are problematic and could be steering people in the wrong direction. In a survey of online articles about preventing Alzheimer’s disease, UBC researchers found many websites offered poor advice and one in five promoted products for sale—a clear … [Read More...]

Healthy Diet, Exercise May Help Keep Alzheimer’s at Bay

(HealthDay News) A healthy diet and regular exercise might be the keys to keeping your brain free of changes that lead to Alzheimer's disease, a small study suggests. Researchers studied 44 patients between the ages of 40 and 85 who had mild memory problems. The investigators found that the brains of those who followed a Mediterranean diet and were physically active had fewer plaques and … [Read More...]

‘Critical Insights’ for Treating, Preventing Alzheimer’s Disease

(Northeastern University) New research led by Northeastern University suggests that Alzheimer's disease may not progress like falling dominoes, as conventional wisdom holds, with one molecular event sparking the formation of plaques throughout the brain. Instead, it may progress like a fireworks display, with a unique flare launching each plaque, one by one. The study, headed by Lee Makowski, … [Read More...]

CAREGIVER’S CORNER

10 Early Signs of Alzheimer’s: When to Call the Doctor

(WebMD) Are you worried about your mental sharpness? Or maybe that of a loved one’s? Mild forgetfulness can be a normal part of aging. If you have trouble remembering someone's name but it comes to you later, that's not a serious memory problem. But if memory problems are seriously affecting your daily life, they could be early signs of … [Read More...]

Mediterranean Diet: A Heart-healthy Eating Plan

(Mayo Clinic) The heart-healthy Mediterranean is a healthy eating plan based on typical foods and recipes of Mediterranean-style cooking. Here's how to adopt the Mediterranean diet. If you're looking for a heart-healthy eating plan, the Mediterranean diet might be right for you. The Mediterranean diet incorporates the basics of healthy eating — … [Read More...]

Alzheimer’s Disease and When to Stop Driving

(Mayo Clinic) If your loved one has Alzheimer's, he or she may not be safe on the road. Explain the risks — then provide other ways to get around. Driving is a powerful symbol of competence and independence, besides being a routine part of adult life. But the focused concentration and quick reaction time needed for safe driving tends to decline … [Read More...]

Alzheimer’s Disease and Planning for Care

(UCSF Memory and Aging Center) The first step in planning care is getting an accurate diagnosis. Diagnosis Seek out a dementia clinic at a university hospital or ask your doctor to refer you to a neurologist with expertise in dementia and neurodegenerative disease. Educate Yourself Learn what you can about dementia and neurodegenerative … [Read More...]

SCIENCE CORNER

Youthful Brains in Older Adults

J Neurosci. 2016 Sep 14;36(37):9659-68. doi: 10.1523/JNEUROSCI.1492-16.2016. Youthful Brains in Older Adults: Preserved Neuroanatomy in the Default Mode and Salience Networks Contributes to Youthful Memory in Superaging. Sun FW1, Stepanovic MR2, Andreano J3, Barrett LF4, Touroutoglou A5, … [Read More...]

Physical Activity, Diet, and Risk of Alzheimer Disease

JAMA. 2009 Aug 12;302(6):627-37. doi: 10.1001/jama.2009.1144. Physical activity, diet, and risk of Alzheimer disease. Scarmeas N1, Luchsinger JA, Schupf N, Brickman AM, Cosentino S, Tang MX, Stern Y. Abstract Context Both higher adherence to a Mediterranean-type diet and more physical … [Read More...]

Midlife Physical Activity and Cognition Later in Life

J Alzheimers Dis. 2016 Sep 2. [Epub ahead of print] Midlife Physical Activity and Cognition Later in Life: A Prospective Twin Study. Iso-Markku P1, Waller K2, Vuoksimaa E3,4, Heikkilä K3, Rinne J5, Kaprio J3,4,5, Kujala UM2. Abstract Background Physical activity has been associated with a … [Read More...]

The Discovery of Alzheimer’s Disease

Dialogues Clin Neurosci. 2003 Mar; 5(1): 101–108. The discovery of Alzheimer's disease Hanns Hippius, MD* Hanns Hippius, Psychiatrische Klinik der LMU, Munich, Germany; Gabriele Neundörfer, MD Gabriele Neundörfer, Psychiatrische Klinik der LMU, Munich, Germany; Abstract On Novembers, 1306, … [Read More...]