IN THE SPOTLIGHT

New Estimate Says 46 Million Americans Headed to Alzheimer’s

(NBC News) Close to 50 million Americans could be in the early stages leading to Alzheimer’s disease right now, according to a new forecast. And 6 million people likely have it now, the team at the University of California Los Angeles calculated. The forecast is based on a lot of supposition as well as some hard data, but it’s the best estimate of how badly Alzheimer’s will affect the … [Read More...]

DAILY NEWS

Alzheimer’s Damage in Mice Reduced with Compound that Targets APOE Gene

(Washington University School of Medicine) People who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease. Now, researchers at Washington University School of Medicine in St. Louis have identified a compound that targets the APOE protein in the brains of mice and protects against damage induced by the Alzheimer's protein amyloid beta. "Scientists have … [Read More...]

Canola Oil Linked to Worsened Memory and Learning Ability in Alzheimer’s Disease

(Temple University Health System) Canola oil is one of the most widely consumed vegetable oils in the world, yet surprisingly little is known about its effects on health. Now, a new study published online December 7 in the journal Scientific Reports by researchers at the Lewis Katz School of Medicine at Temple University (LKSOM) associates the consumption of canola oil in the diet with worsened … [Read More...]

Researchers Identify First Brain Training Exercise Positively Linked to Dementia Prevention

(Indiana University) Aging research specialists have identified, for the first time, a form of mental exercise that can reduce the risk of dementia. The cognitive training, called speed of processing, showed benefits up to 10 years after study participants underwent the mental exercise program, said Frederick W. Unverzagt, PhD, professor of psychiatry at Indiana University School of … [Read More...]

Obesity Increases Dementia Risk

(University College London) People who have a high body mass index (BMI) are more likely to develop dementia than those with a normal weight, according to a new UCL-led study. The study, published in the Alzheimer's & Dementia journal, analysed data from 1.3 million adults living in the United States and Europe. The researchers also found that people near dementia onset, who then go on to … [Read More...]

New Easy-To-Use Tool Can Help Determine Alzheimer’s Risk

(Canadian Medical Association Journal) A simple new tool that tracks cognitive performance in adults aims to help physicians identify people who may be on the path to Alzheimer disease or another form of dementia. The tool, called the QuoCo (cognitive quotient), is published in CMAJ (Canadian Medical Association Journal). "Similar to 'growth charts' used in pediatrics, the QuoCo cognitive charts … [Read More...]

CAREGIVER’S CORNER

Adapting Activities for People with Alzheimer’s Disease

(NIH) Doing things we enjoy gives us pleasure and adds meaning to our lives. People with Alzheimer’s disease need to be active and do things they enjoy. However, don’t expect too much. It’s not easy for them to plan their days and do different tasks. People with Alzheimer’s may have trouble deciding what to do each day, which could make them … [Read More...]

Holidays and Alzheimer’s Families

(Alzheimer's Association) The holidays are a time when family and friends often come together. But for families living with Alzheimer's and other dementias, the holidays can be challenging. Take a deep breath. With some planning and adjusted expectations, your celebrations can still be happy, memorable occasions. Familiarize Others with the … [Read More...]

Recognizing Alzheimer’s Disease

(Helpguide.org) Alzheimer's Disease can be caught in the early stages—when the best treatments are available—by watching for telltale warning signs. If you recognize the warning signs in yourself or a loved one, make an appointment to see your physician right away. Brain imaging technology can diagnose Alzheimer's early, improving the opportunities … [Read More...]

Perfect Gifts for Seniors in Assisted Living Facilities

(Ezine) It's no secret that finding the perfect gift for a senior citizen is a bit difficult, but shopping for a present for someone living in an assisted living facility is a little more tedious. Individuals in long-term care facilities may not need much more than the everyday necessities. However, when it comes birthdays or Christmas presents, … [Read More...]

Lifelong Strategies for Preventing Dementia

(Mayo Clinic) Q: Do puzzles and other activities or apps that claim to lower one's risk of developing dementia actually work? Are there other things people can do to decrease the risk? A: Doing activities that stimulate your brain may reduce your risk of developing dementia. But it's more complex than taking up puzzles or computer games at age … [Read More...]

SCIENCE CORNER

Alzheimer’s Disease Prevention: From Risk Factors to Early Intervention

Alzheimers Res Ther. 2017 Sep 12;9(1):71. doi: 10.1186/s13195-017-0297-z. Alzheimer's disease prevention: from risk factors to early intervention. Crous-Bou M1, Minguillón C1, Gramunt N1,2, Molinuevo JL3,4. Abstract Due to the progressive aging of the population, Alzheimer's disease (AD) is becoming a healthcare burden of epidemic proportions for which there is currently no cure. Disappointing results from clinical … [Read More...]

Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging

Mayo Clin Proc. 2011 Sep;86(9):876-84. doi: 10.4065/mcp.2011.0252. Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Ahlskog JE1, Geda YE, Graff-Radford NR, Petersen RC. Abstract A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords exercise and … [Read More...]

Prolonged Sleep Duration as Marker of Early Neurodegeneration Predicting Dementia

Neurology. 2017 Feb 22. pii: 10.1212/WNL.0000000000003732. doi:[Epub ahead of print] Prolonged sleep duration as a marker of early neurodegeneration predicting incident dementia. Westwood AJ1, Beiser A1, Jain N1, Himali JJ1, DeCarli C1, Auerbach SH1, Pase MP2, Seshadri S2. Abstract OBJECTIVE To evaluate the association between sleep duration and the risk of incident dementia and brain aging. METHODS Self-reported … [Read More...]

Female Sex, Early-Onset Hypertension, and Risk of Dementia

Neurology. 2017 Oct 31;89(18):1886-1893. doi: 10.1212/WNL.0000000000004602. Epub 2017 Oct 4. Female sex, early-onset hypertension, and risk of dementia. Gilsanz P1, Mayeda ER1, Glymour MM1, Quesenberry CP1, Mungas DM1, DeCarli C1, Dean A1, Whitmer RA2. Abstract Objective To evaluate the association of early-adulthood and mid-adulthood hypertension with dementia in men and women. Methods We evaluated 5,646 members of … [Read More...]